Products

MTA-12 and Custom Arrays

Assay Principle & Procedure

Product Specifications for:

MTA-12 / Custom Arrays

Amphetamine

Barbiturates

Benzodiazepines

Buprenorphine

Cannabinoids

Cocaine

Fentanyl

Ketamine

MDMA

Methadone

Methamphetamine

Opiates

Oxycodone

Phencyclidine

Propoxyphene

Tramadol

Tricyclic Antidepressants

MTA-12™ Drug Test System Performance Characteristics

Careful attention to manufacturing processes and quality of materials has allowed Venture Labs to offer this robust drug test system, as indicated by the following performance characteristics.

Sample Standard Curves

Stability

Precision

Spike & Recovery

Cross Reactivity


Example Standard Curves
These standard curves are for illustration only and should not be used to calculate unknowns.

Calibrator Concentration (ng/mL)
Analyte
0
10
20
40
80

Amphetamine

2.569
1.618
1.220
0.860
0.590

Barbiturates

2.024
1.236
0.982
0.813
0.605

Benzodiazepines

2.305
1.416
1.260
1.073
0.954

Cocaine

2.373
1.500
1.038
0.718
0.437
Ketamine
2.306
1.483
1.234
0.993
0.808
MDMA
2.071
1.362
1.139
0.785
0.610

Methadone

2.030
1.340
1.068
0.795
0.609

Methamphetamine

2.178
1.537
1.168
0.800
0.533

Opiates

2.080
1.381
1.068
0.732
0.527

Oxycodone

2.402
1.505
1.289
1.054
0.747

Propoxyphene

2.071
1.362
1.139
0.785
0.610
Tramadol
2.205
1.480
1.123
0.752
0.455

Tricyclic Antidepressants

2.115
1.447
1.267
1.005
0.742

Analyte
0
1
2
4
8

Cannabinoids

2.051
1.573
1.268
1.096
0.840

Phencyclidine

2.017
1.386
1.091
0.775
0.512

Analyte
0
0.5
1
2
4

Buprenorphine

2.301
1.217
0.859
0.624
0.460

Calibrator Concentration (pg/mL)
Analyte
0
50
100
200
400

Fentanyl

2.176
1.541
1.170
0.626
0.361

 

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Precision

Within-run precision was determined by running 32 replicates of five different levels in a single run. The %CVs(absorbance) at each level are shown below.

%CV (Absorbance)

Analyte

Neg
10 ng/mL
20 ng/mL
40 ng/mL
80 ng/mL

Amphetamine

4.8
6.5
11.2
6.2
10.0

Barbiturates

3.4
4.6
7.4
7.5
7.5

Benzodiazepines

2.2
3.7
4.0
4.5
5.1

Cocaine

5.0
2.8
4.1
2.8
3.9

Ketamine

2.8
3.6
3.7
1.6
3.0

MDMA

3.4
5.8
6.1
7.1
7.8

Methadone

2.8
4.5
4.0
4.5
3.7

Methamphetamine

3.3
3.7
3.3
3.2
3.7

Opiates

4.1
7.2
3.9
5.5
5.8
Oxycodone
3.1
4.4
4.8
5.4
5.2
Propoxyphene
3.4
5.8
6.1
7.1
7.8
Tramadol
2.8
5.8
6.0
4.9
5.0
Tricyclics
2.8
2.3
3.5
4.2
6.3

Neg
1 ng/mL
2 ng/mL
4 ng/mL
8 ng/mL

Cannabinoids

2.3
2.8
6.1
6.8
3.0

Phencyclidine

2.8
6.3
6.8
6.8
5.3

Neg
0.5 ng/mL
1 ng/mL
2 ng/mL
4 ng/mL

Buprenorphine

5.1
3.0
3.8
5.2
6.7

Neg
50 pg/mL
100 pg/mL
200 pg/mL
400 pg/mL

Fentanyl

2.0
3.4
1.6
1.9
4.8

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Stability :

The MTA-12™ drug test system kit is stable for 1 year under recommended storage conditions. Please check the expiration date on the lower-right-hand corner of the kit label.

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Spike & Recovery

Drug analytes were spiked into buffer, assayed and quantitated from a standard curve. The spike drug concentration and recovered drug level in ng/mL is shown below:

Added Concentration (ng/mL)

12.5
17.5
25.0
35.0
50.0
70.0

Analyte

Measured Concentration (ng/mL)

Amphetamine

10.7
17.2
26.8
35.0
45.0
60.0

Barbiturates

10.5
15.0
21.0
30.0
48.0
64.0

Benzodiazepines

12.0
18.5
31.5
34.0
51.0
59.0

Cocaine

12.8
17.5
23.0
34.5
54.0
63.0
Ketamine
14.0
17.5
24.5
32.0
47.0
72.0
MDMA
14.9
21.8
28.1
36.0
48.5
73.0

Methadone

10.5
16.2
26.0
32.0
53.0
72.0

Methamphetamine

12.6
17.7
28.3
35.5
45.0
62.0

Opiates

12.2
18.6
28.8
38.2
50.0
69.0

Oxycodone

11.5
16.5
22.5
35.0
52.0
75.0

Propoxyphene

14.9
21.8
28.1
36.0
48.5
73.0
Tramadol
12.3
18.5
25.0
33.0
50.0
64.0

Tricyclics

13.1
16.0
26.0
31.0
48.0
68.0


Analyte

Recovery (%)

Amphetamine

85.6
98.3
107
100
90.0
85.7

Barbiturates

84.0
88.2
84.0
85.7
96.0
91.4

Benzodiazepines

96.0
106
126.0
97.1
102
84.3

Cocaine

102
100
92.0
98.6
108
90.0
Ketamine
112
100
98.0
91.4
94.0
103
MDMA
119
124
112
103
97.0
104

Methadone

84.0
92.5
104
91.4
106.0
103

Methamphetamine

101
101
113
101
90
88.5

Opiates

97.0
106
115
109
100
98.5

Oxycodone

92.0
94.3
90.0
100
104
107

Propoxyphene

119
124
112
103
97.0
104
Tramadol
98
106
100
94.3
100
91.4

Tricyclics

105
91.5
104
88.6
96.0
97.1


Added Concentration (ng/mL)

1.25
1.75
2.5
3.5
5.0
7.0

Analyte

Measured Concentration (ng/mL)

Cannabinoids

1.25
1.9
2.7
3.5
4.6
7.0

Phencyclidine

1.2
1.7
2.45
3.2
5.1
7.1

Recovery (%)

Cannabinoids

100
109
106
100
92
100

Phencyclidine

96.0
97.1
98.0
91.4
102
101


Added Concentration (ng/mL)

0.625
0.875
1.25
1.75
2.5
3.5

Analyte

Measured Concentration (ng/mL)

Buprenorphine

0.65
0.825
1.25
1.8
2.3
3.3

Recovery (%)

Buprenorphine

104
94.3
100
103
92
94.3


Added Concentration (pg/mL)

62.5
87.5
125
175
250
350

Analyte

Measured Concentration (pg/mL)

Fentanyl

63
96
124
158
218
300

Recovery (%)

Fentanyl

101
110
99.2
90.3
87.2
85.7

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Cross Reactivity & Interfering Substances
The following 164 compounds were tested in the MTA™ kit at the concentrations [ng/mL] shown. Compounds which tested positive were re-assessed with each individual assay. For assay specific cross reactivity, please see the individual cross reactivity specifications for each assay.

 

Acetaminophen

50,000

N-Hydroxy MDA

50,000

Acetylsalycylic Acid

50,000

a-Hydroxyalprozolam

10,000

Alprazolam

50,000

4-hydroxy-PCP
500

7-Aminoclonazepam

50,000

11-hydroxy-delta-9-THC
500

7-Aminoflunitrazepam

50,000

Ibuprofen

50,000

Amitriptylline

50,000

Imipramine

50,000

Amobarbital

50,000

(+/-) Isoproterenol

50,000

d-Amphetamine

10,000

Isoxsuprine

50,000

l-Amphetamine

1,000

Ketamine 50,000

Ampicillin

50,000

Lidocaine

50,000

Aprobarbital

50,000

Lorazepam

10,000

Ascorbic Acid

50,000

Lormetazepam

50,000

Aspartame

50,000

Maprotiline

50,000

Atropine

50,000

MDA

50,000

Benzocaine

50,000

MDE

10,000

Benzoyl Ecgonine

10,000

MDMA

10,000

Bromazepam

50,000

Medazepam

50,000

Buprenorphine
10,000

Meperidine

10,000

Butabarbital

50,000

Mephentermine

50,000

Butalbital

50,000

Mephobarbital

100,000

Caffeine

50,000

Methadol

50,000

Cannabidiol

5,000

(+) Methadone

10,000

Cannabinol

5,000

(+/-) Methadone

5,000

Carbamazepine

50,000

d-Methamphetamine

10,000

Chlordiazepoxide

50,000

l-Methamphetamine

10,000

Chloroquine

50,000

Metharbital

100,000

Chlorothiazide

50,000

N-Methyl Ephedrine

50,000

(+) Chlorpheniramine

50,000

Methylphenidate

50,000

(+/-) Chlorpheniramine

50,000

Midazolam

10,000

Chlorpromazine

50,000

6-Mono-acetylmorphine

10,000

Clobazam

50,000

Morphine

10,000

Clomipramine

50,000

Morphine-3-beta-D-glucuronide

25,000

Clonazepam

50,000

Nalorphine

10,000

Clorazepate

50,000

Naloxone

50,000

Clorazepam

25,000

(+) Naproxen

50,000

Cocaethylene

50,000

Nicotine

50,000

Cocaine

5,000

Nitrazepam

50,000

Codeine

25,000

Norclomipramine
50,000

(-) Cotinine

50,000

Norketamine
50,000

Creatine

50,000

Norpropoxyphene

5,000

Cyclobenzaprine

50,000

Nortriptyline

50,000

Cyclopentobarbital

50,000

Oxalic Acid

50,000

Delorazepam

50,000

Oxazepam

50,000

Delta-8-tetrahydrocannabinol

1,000

Oxazolam

50,000

Delta-8-THC-acid

500

Oxycodone

10,000

Delta-9-tetrahydrocannabinol

1,000

Oxymorphone

10,000

Delta-9-THC-acid

1,000

PCM (Morpholine PCP Analog)

10,000

Demoxepam
50,000

Pentobarbital

50,000

Desalkylflurazepam
50,000

Perphenazine

100,000

Desipramine

50,000

Phencyclidine

1,000

Desmethyl Diazepam

10,000

Pheniramine

50,000

Despropionylfentanyl
50,000

Phenobarbital

100,000

Dexbrompheniramine

50,000

Phenothiazine

25,000

Dextromethorphan

50,000

Phentermine

50,000

Diacetylmorphine

10,000

L-Phenylalanine

50,000

Diallylbarbital

50,000

L-Phenylephrine

50,000

Diazepam

10,000

B-Phenylethylamide

50,000

4-Dimethylaminoantipyrine

50,000

Phenylpropanolamine

50,000

Diphenhydramine

50,000

Prazepam

10,000

Diphenylhydantoin

50,000

Primidone

50,000

Dopamine

50,000

Procaine

50,000

Doxepin

50,000

Promethazine

50,000

Ecgonine

10,000

d-Propoxyphene

5,000

Ecgonine Methyl Ester

10,000

Protriptyline

50,000

EDDP

50,000

(+/-) Pseudoephedrine

50,000

(-) Ephedrine

50,000

(R, 2R) Pseudoephedrine

50,000

(-) Epinephrine

50,000

Quinidine

50,000

(+/-) Epinephrine

50,000

Ranitidine

50,000

Erythromycin

50,000

Secobarbital

25,000

Estazolam

50,000

Sulindac

50,000

Ethylmorphine

25,000

Talbutal

50,000

Fenfluramine

10,000

Temazepam

50,000

Fentanyl

10,000

Thebaine

50,000

Flunitrazepam

10,000

Theophylline

50,000

Flurazepam

10,000

Thiopental

50,000

Furosemide

50,000

Thioridazine

50,000

D (+) Glucose

50,000

Tramadol
10,000

Guaiacol Glycerol

50,000

Triazolam

50,000

Halazepam

10,000

Trifluoperazine

50,000

Hexobarbital

50,000

Trimethobenzamide

50,000

Hydrocodone

10,000

Trimipramine

50,000

Hydromorphone

10,000

Tyramine

50,000

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